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Decrease in CD8+CD45+CCR7+CD62L+ T cells in individuals vaccinated with Sinovac-CoronaVac following COVID-19 infection.
Fonseca, Dâmaris C S C; Rocha, Mirtes C B; Pereira, Lucca A; Botega, Leticia P; Cutrim, Susanne C P F; Silva, Fabiano V; Batista, Flávio D; Rêgo, Adriana S; Falcai, Ângela; Lima-Neto, Lídio G; Santos, Ana Paula S A; Carvalho, Rafael C; Sousa, Eduardo M.
Clin Immunol ; 242: 109092, 2022 09.
Article in English | MEDLINE | ID: covidwho-2035867

ABSTRACT

Vaccines induce antibodies, but T cell responses are also important for protection against Coronavirus disease 2019. Here, we analyzed the frequency of memory T cells in infected and/or vaccinated individuals and observed a decrease in central memory T cells in individuals who were vaccinated following COVID-19 infection.


Subject(s)
CD8-Positive T-Lymphocytes , COVID-19 Vaccines , COVID-19 , Antibodies, Viral , CD8-Positive T-Lymphocytes/cytology , COVID-19/prevention & control , COVID-19 Vaccines/immunology , Humans , Memory T Cells/cytology , Vaccination
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